Safety and efficacy of restarting antiplatelet therapy after intracerebral hemorrhage

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Antiplatelet therapy may be continued after intracerebral hemorrhage.

Fortunately, we live and work in an era when several interventions are known to prevent or treat ischemic stroke. For patients like this 81-year-old woman, secondary prevention of vascular disease with aspirin provides statistically and clinically significant absolute reductions in all serious vascular events, in all stroke, and in coronary events that offset the nonsignificant increase in the ...

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Restarting Anticoagulant Therapy After Intracranial Hemorrhage

Atrial fibrillation increases the risk of stroke 3to 5-fold and is implicated in about 15% of all strokes every year. Anticoagulation therapy has been proven to be efficacious in reducing incident stroke and systemic embolism in patients with atrial fibrillation and mechanical heart valves. However, the benefits of anticoagulation must be carefully weighed against the increased risk of intracra...

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Efficacy and Safety of Dual Antiplatelet Therapy After Complex PCI.

BACKGROUND Optimal upfront dual antiplatelet therapy (DAPT) duration after complex percutaneous coronary intervention (PCI) with drug-eluting stents (DES) remains unclear. OBJECTIVES This study investigated the efficacy and safety of long-term (≥12 months) versus short-term (3 or 6 months) DAPT with aspirin and clopidogrel according to PCI complexity. METHODS The authors pooled patient-leve...

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Prescribing antiplatelet medicine and subsequent events after intracerebral hemorrhage.

BACKGROUND AND PURPOSE Antiplatelet medicines are commonly perceived as contraindicated after intracerebral hemorrhage (ICH). Many ICH patients have or will have indications for antiplatelet therapy. This observational study describes the level of antiplatelet prescribing and rate of subsequent events after ICH in Tayside, Scotland. METHODS This study used record-linkage of an existing stroke...

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Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage.

BACKGROUND Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high mortality and disability rate and accounts for about 10-15% of all strokes. The oppression and destruction by hematoma to brain tissue cause the primary brain injury. The inflammation and coagulation response after ICH would accelerate the formation of brain edema around hematoma, resulting in a more severe and ...

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ژورنال

عنوان ژورنال: Annals of Translational Medicine

سال: 2019

ISSN: 2305-5839,2305-5847

DOI: 10.21037/atm.2019.08.96